Patients with immune anti-D, anti-K or anti-c, must have a titration performed every 4 weeks until 28 weeks of pregnancy.  After 28 weeks, a titration should be performed every 2 weeks.  Clinical staff are responsible for ensuring repeat samples are sent when required.

Other antibody specificities (not anti-D, anti-c or anti-K) that have the possibility to cause HDFN require a titration upon initial identification of the antibody, or first presentation in the pregnancy if a known historical antibody, and at 28 weeks.  After 28 weeks no further antibody titrations are required.

Occasionally, an antibody titration may be requested (due to ultrasonic abnormalities or precious pregnancies) but is not normally indicated. This request must be discussed with a laboratory haematology consultant or registrar (03 9496 6206 or 03 9496 5981).

Up to three red cell antigens are tested.

• Surname AND given name
• Date of birth
• UR number and/or Address
• Date and time
• Sign or initial the specimen tube

• Surname AND given name
• Date of birth
• UR number and/or Address
• Date and time
• Complete and sign the request form declaration

All details including signatures and date/time on specimen tube and request form must match.

For patients under the care of the following : Goulburn Valley Health, Swan Hill District Health, Mildura Base Public Hospital, Echuca Regional Health, Nathalia Cobram Numurkah Health specimens must be HAND LABELLED.

Pre-printed labels are accepted for other health services. If a pre-printed label is used on the specimen, it MUST bear the collector's signature and date and time of collection.

See "Pre-Transfusion Specimen Requirements (PDF)" below for further details.