Haematolymphoid Disorders and Myeloproliferative Neoplasms (MPN) NGS Panel (Tissue) Test | Austin Pathology

View the new Tube Guide and Swab Guides. You can also order hard copies via our Order Form.

Austin Pathology

Test Directory

Search in the bar above for available tests.
Type any letter of the alphabet to be presented with all available results for that letter.

Haematolymphoid Disorders and Myeloproliferative Neoplasms (MPN) NGS Panel (Tissue)

Alternate Names	Myeloid NGS, Lymphoid NGS, AMYNGS, Haematolymphoid Disorders NGS Panel, Myeloproliferative Neoplasms (MPN) NGS Panel, MPN, MPN NGS Panel
Test Code	AMYNGS
Testing Laboratory	Molecular Diagnostics - Genetics
Specimen Type	Tissue
Container Type	Glass slides Tumour Block
Medicare Rebate	Yes
Out of Pocket Costs	Please note: Medicare Rebate for this test is subject to conditions. Patients may receive an invoice: Haematolymphoid Disorders NGS Panel Clinical Indication: Suspected myeloid malignancy Medicare (Fully Covered)- MBS 73447 Non-Medicare eligible - $829.20 Clinical Indication: Suspected lymphoid malignancy Medicare (Fully Covered)- MBS 73448 Non-Medicare eligible - $829.20 Clinical Indication: Primary Myelofibrosis, transplant eligible Medicare (Fully Covered)- MBS 73399 Non-Medicare eligible - $700.00 Myeloproliferative Neoplasm (MPN) NGS Panel Clinical Indication: Myeloproliferative neoplasm (PV / ET) Medicare (Fully Covered) - MBS 73398 *Non-Medicare eligible- $500.00* *For non-Medicare eligible patients - Patient Financial Consent Form must be completed.* Fee above is an indication only; please contact testing laboratory for up-to date cost.
Ordering Information	Please refer to Molecular Genetics - Austin Pathology for specific testing details and request form for ordering. Haematolymphoid Disorders NGS Panel Gene List (73): ABL1, ASXL1, BAD, BAX, BCL2, BCL2L1, BCOR, BIRC3, BRAF, BTK, CALR, CARD11, CBL, CCND1, CD274, CD79B, CEBPA, CSF3R, CXCR4, DDX41, DNMT3A, EGR2, ETNK1, ETV6, EZH2, FBXW7, FLT3, FYN, GATA1, GATA2, ID3, IDH1, IDH2, IRF8, JAK2, KIT, KRAS, MAP2K1, MEN1, MPL, MYD88, NOTCH1, NOTCH2, NPM1, NRAS, PDCD1LG2, PHF6, PIM1, PLCG1, PLCG2, PPM1D, PTEN, PTPN11, RHOA, RUNX1, SETBP1, SF3B1, SH2B3, SMARCA2, SMARCA4, SRSF2, STAG2, STAT3, STAT5B, STAT6, TET2, TP53, U2AF1, UBA1, UBTF, WT1, XPO1, ZRSR2. Myeloproliferative Neoplasm (MPN) NGS Panel Gene List (23): ASXL1, CALR, CBL, CSF3R, DNMT3A, ETNK1, EZH2, IDH1, IDH2, JAK2, KIT, KRAS, MPL, NRAS, RUNX1, SETBP1, SF3B1, SRSF2, SH2B3, TET2, TP53, U2AF1 Haematolymphoid Disorders and Myeloproliferative Neoplasms (MPN) NGS Panel utilises massively parallel sequencing technology to assess genetic variants (also referred to as mutations) that are important in different haematolymphoid disorders. Genes assessed in these panels are currently known to have important diagnostic, prognostic and therapeutic implications. Any specific FLT3 or NPM1 requests must add test code AFLTNP. If NPM1 MRD (Minimal Residual Disease) is requested using ANPM1 test code, sample must be received within 48 hours of collection. For JAK2 exon 14 requests use test code AJAK2, unless JAK2 exon 12 stated then use test code AMYNGS. Note that some of these genes are also tested using the solid tumour NGS panel for colorectal cancer, lung cancer or melanoma. Please refer to relevant solid tumour NGS panels.
Collection Instructions	TISSUE Resection: 1 x H&E stained & 6 x unstained slides (5µm) OR Small Biopsy: 1 x H&E stained & 10 x unstained slides (5µm) OR FFPE tissue block (at least 10% tumour nuclei) Copy of the histology or cytology report Instructions for: External Referring Laboratories If DNA is the preferred specimen type, a minimum of 20μL at 50ng/μL is required.
Transport Instructions	Transport ambient at room temperature
Storage Instructions	Store refrigerated at 4°C
Testing Frequency	Fortnightly
Min Test Volume	None
Add On Test Suitability	Contact Molecular Diagnostics - Genetics on 03 9496 5657 to confirm add on suitability.

Container ID	CMOL
CSR Instructions	Instructions for: Metropolitan & Regional Specimen Receptions For single gene MYD88 requests use test code AMYD88, unless both MYD88 and CXCR4 are stated then use test code AMYNGS.
Laboratory Instructions	None
Accredited Test	Yes

These PDF documents can be downloaded for your reference

Order of Draw (PDF)

Swab Collection Guide (PDF)

Pre-Transfusion Specimen Requirements (PDF)

Requirements for Pathology Service (PDF)