Myeloid Gene Mutation Analysis (could also be requested individually or as a MPN - Myeloproliferative Neoplasm - panel) for the following genes:

ASX1, BRAF, CALR, CBL, CEBPA, CSF3R, CXCR4, DDX41, DNMT3A, ETKN1, EZH2, FBXW7, FLT3, GATA1, GATA2, IDH1, IDH2, JAK2, KIT, KRAS, MPL, MYD88, NOTCH1, NPM1, NRAS, PPM1D, PTEN, RHOA, RUNX1, SETBP1, SF3B1, SRSF2, STAT3, STAT5B, STAT6, TET2, TP53, U2AF1, WT1

The myeloid NGS panel simultaneously detects mutations in 31 genes important for diagnostic, prognostic or therapeutic decisions in myeloid malignancies. 

The MPN Myeloproliferative Neoplasm panel simultaneously detects mutations in 9 genes

ASX1, CALR, CSF3R, JAK2, KIT, MPL, SETBP1, SF3B1, SRSF2

To order, use the Molecular Haematology Request form: Molecular Haematology Test Request FormV5.pdf

For pricing refer to: Molecular Haematology Tests and Pricing V5.pdf

Any specific FLT3 or NPM1 requests also add test code AFLT3.

If NPM1 MRD (Minimal Residual Disease) is requested this is a send out to Alfred Hospital using MISCSO test code and must be received by the external laboratory within 48 hours of collection.

For JAK2 requests use test code AJAK2 instead unless JAK2 exon 12 stated then use test code AMYNGS.

Note that some of these genes are also tested using the solid tumour NGS panel for colo-rectal cancer, lung cancer or melanoma.

Store sample in CSR fridge.