Please note: Medicare Rebate for this test is subject to conditions. Patients may receive an invoice:

Myeloid NGS Panel

• Fully covered by Medicare - MBS 73447
• Non-Medicare eligible - $829.20 

Myeloproliferative Neoplasm (MPN) NGS Panel

• MBS 73398
• Non-Medicare eligible- $500.00

Primary Myelofibrosis (MF), transplant eligible NGS Panel

• Fully covered by Medicare - MBS 73399
• Non-Medicare eligible - $700.00

 
For non-Medicare eligible patients - Patient Financial Consent Form must be completed.

Fee above is an indication only; please contact testing laboratory for up-to date cost. 

Please refer to Molecular Genetics - Austin Pathology for specific testing details and request form for ordering.

Myeloid Gene Mutation Analysis (could also be requested individually or as a MPN - Myeloproliferative Neoplasm - panel) for the following genes:

ASXL1, BRAF, CALR, CBL, CEBPA, CSF3R, CXCR4, DDX41, DNMT3A, ETNK1, EZH2, FBXW7, FLT3, GATA1, GATA2, IDH1, IDH2, JAK2, KIT, KRAS, MPL, MYD88, NOTCH1, NPM1, NRAS, PPM1D, PTEN, RHOA, RUNX1, SETBP1, SF3B1, SRSF2, STAT3, STAT5B, STAT6, TET2, TP53, U2AF1, WT1

The myeloid NGS panel simultaneously detects mutations in 39 genes important for diagnostic, prognostic or therapeutic decisions in myeloid malignancies. 

The MPN Myeloproliferative Neoplasm panel simultaneously detects mutations in 8 genes: ASXL1, CALR, CSF3R, JAK2, KIT, MPL, IDH1, IDH2

Any specific FLT3 or NPM1 requests must add test code AFLTNP.

If NPM1 MRD (Minimal Residual Disease) is requested using ANPM1 test code, sample must be received within 48 hours of collection.

For JAK2 exon 14 requests use test code AJAK2, unless JAK2 exon 12 stated then use test code AMYNGS.

Note that some of these genes are also tested using the solid tumour NGS panel for colo-rectal cancer, lung cancer or melanoma.

BLOOD

• A DEDICATED 4 mL EDTA tube must be collected and should not be shared with other tests of the same sample type.
  
  

Instructions for: External Referring Laboratories

• If DNA is the preferred specimen type, a minimum of 20μL at 50ng/μL is required.

Contact Molecular Diagnostics - Genetics on 03 9496 5657 to confirm add on suitability.